Untangling the ErbB signalling network. Platelet-derived growth factor induces apoptosis in growth-arrested murine fibroblasts. Impact of EGFR expression on colorectal cancer patient prognosis and survival. High-dose estrogen as salvage hormonal therapy for highly refractory metastatic breast cancer: Sci Signal ; 6:
The paradoxical functions of EGFR during breast cancer progression
Doctors are studying whether these targeted medicines could be used to treat EGFR-positive breast cancer. In subsequent studies, the combination of cetuximab with antimicrotubule agents or topoisomerase inhibitors did not increase patient overall survival as compared with these chemotherapies alone, leading to premature trial termination. Panitumumab, gemcitabine, and carboplatin as treatment for women with metastatic triple-negative breast cancer: Gefitinib treatment in what is egfr in breast cancer and hormone receptor-negative advanced breast cancer. Below we review some of the established findings that support the existence of the EGFR paradox during BC growth, dissemination and metastasis.
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Gefitinib treatment in hormone-resistant and hormone receptor-negative advanced breast cancer. Was this article helpful? Evidence for EGF-induced anoikis. STAT3 activation is a critical step in gpmediated terminal differentiation and growth arrest of a myeloid cell line.