Fatigue in breast cancer patients

Patients were treated with six cycles of 5-Flurouracil, Doxorubicin, and Cyclophosphamide with standard dose schedule in 21—28 days interval according to current practice fatigue in breast cancer patients of the study hospital. But on analyzing the FACIT Total score, we found that scores were increased from cycle one to cycle two significantly, but from cycle two to cycle six, the scores were significantly decreased. More specifically, lower the hemoglobin level, lower was the score. Table 1 Patients' characteristics.

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Fatigue in Breast Cancer Patients on Adjuvant Treatment: Course and Prevalence

Significant cofactors were also searched for. Multimodal approach is helpful in managing fatigue. Fatigue increases during chemotherapy and or EBRT. No significant correlation was evident in any of the cofactors except anemia P 0. A total of 79 eligible subjects were taken for this study.

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Adjuvant chemotherapy is part of the standard treatment in a large subset of patients. Concentrated RBC was transfused for correction of anemia. More specifically, lower the hemoglobin level, lower was the score. Correction of anemia improved the scores significantly, contradicting the results by So-Osman et al. These MID values can be used to aid the interpretation of group differences and changes in HRQoL over time, and they can be useful in sample size calculations.

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